Plastics jam your cells' cleanup. Spermidine keeps it going.

Microplastics have been detected in the blood of 77% of healthy adults.

Based on recent research, you're likely carrying about 7 grams of microplastics in your brain: the weight of a plastic spoon.

When your cells detect nanoplastics, they try to clear them using autophagy, the process every cell uses to take out the trash.

But plastics jam the system. The recycling machinery stalls, mitochondria get damaged, and inflammation spikes.

Spermidine keeps the autophagy going, isolating the plastic particles and continuing the cleanup. It also triggers mitophagy, clearing the damaged mitochondria so they don't sap your energy.

Spermidine and sulforaphane are two of the only supplements shown to help remove microplastics from the body.

SPMD-99 delivers 20 mg per serving of 99+% pure spermidine, the highest dose in any leading brand.

See every brand's lab report.

Spermidine is also linked to nearly 6 years of longer life, and it's behind fuller hair, stronger nails and firmer skin.

In a placebo-controlled study lasting 90 days, spermidine pushed significantly more follicles back into active growth. Hair is usually where people see it first.

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The Opus Longevity Team